Regional Association of Methylome variability with the Exposome
and geNome
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Documentation for package ‘RAMEN’ version 2.99.0
Help Pages
| findCisSNPs | Find cis SNPs around a set of Variable Methylated Loci (VML) |
| findVML | Identify Variable Methylated Loci in microarrays |
| lmGE | Fit linear G, E, G+E and GxE models and select the winning model |
| medCorVMR | Compute the median probe methylation pearson correlation for each Variable Methylated Region (VMR). |
| nullDistGE | Simulate a delta R squared null distribution of G and E effects on DNAme variability |
| selectVariables | Selection of relevant environment and genotype variables associated with Variably Methylated Loci (VML) |
| summarizeVML | Summarize the methylation states of Variable Methylated Loci (VML) |
| test_covariates | Concomitant variable example data set |
| test_environmental_matrix | Environmental exposures example data set |
| test_genotype_information | Genotype metadata example data set |
| test_genotype_matrix | Genotype matrix example |
| test_methylation_data | Methylation data matrix example |
| ultrastable_cpgs | Ultrastable probes |