Enabling Cell-Type Deconvolution of Proteomics Data


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Documentation for package ‘proteoDeconv’ version 0.1.2

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convert_to_tpm Convert protein abundance data to TPM-like normalization
create_phenoclasses Create phenoclasses matrix for cell type deconvolution
create_signature_matrix Create signature matrix using CIBERSORTx
deconvolute Deconvolute protein data using multiple algorithms
deconvolute_bayesdebulk Deconvolute bulk proteome data using BayesDeBulk
deconvolute_cibersort Deconvolute mixture data using CIBERSORT
deconvolute_cibersortx Deconvolute using CIBERSORTx Docker image
deconvolute_epic Deconvolute bulk data using EPIC
extract_identifiers Extract primary identifiers from e.g. protein groups
handle_duplicates Handle duplicate identifiers in an expression matrix
handle_missing_values Handle missing values
handle_scaling Handle scaling of protein abundance data
map_cell_groups Map column names to cell type groups using patterns
simulate_data Simulate artifical mixtures from bulk proteome measurements
unlog2_data Convert data from log2 scale to linear scale
update_gene_symbols Update gene symbols in a matrix to approved HGNC nomenclature