Proximity-Associated Changes in Expression for Spatial Transcriptomics


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Documentation for package ‘PACE’ version 0.99.20

Help Pages

ambientField Build the ambient contamination field
ambientField-method Build the ambient contamination field
anchorGenes Contamination anchor genes per cell type
buildNeighbourhood Build the neighbourhood kernels
buildNeighbourhood-method Build the neighbourhood kernels
cellContamination Per-cell contamination
cellContamination-method Per-cell contamination
cellTypes Cell types modelled
cellTypes-method Cell types modelled
compactFit Drop the per-cell matrices from a fit
fitState Raw solver state
fitState-method Raw solver state
neighbourSlopes Shrunken neighbour proximity slopes
neighbourSlopes-method Shrunken neighbour proximity slopes
neighbourSlopes<- Shrunken neighbour proximity slopes
neighbourSlopes<--method Shrunken neighbour proximity slopes
paceDecompose Variance decomposition
paceDecompose-method Variance decomposition
paceDrivers Per-pair driver scores
paceDrivers-method Per-pair driver scores
PACEFit PACEFit: a fitted PACE model
paceFit Fit a PACE model to a SpatialExperiment
PACEFit-class PACEFit: a fitted PACE model
paceFit-method Fit a PACE model to a SpatialExperiment
paceModel Fit the PACE model
paceModel-method Fit the PACE model
paceModelGaussian Fit the PACE model to continuous intensities
paceModelGaussian-method Fit the PACE model to continuous intensities
paceParams Fitting parameters
paceParams-method Fitting parameters
paceShrink Shrink the neighbour slopes
paceShrink-method Shrink the neighbour slopes
pairVariance Pairwise spatial variance table
pairVariance-method Pairwise spatial variance table
plotDecomposition Per-focal variance decomposition plot
plotDrivers Per-pair driver composite
plotPairHeatmap Pairwise spatial-percent heatmap
plotProximity Expression versus number of neighbours (per-bin boxplot)
plotResponseCurve Response curve: binned means with the PACE slope overlaid
plotResponseMap Tissue maps and scatters for one exemplar image per arm
show-method PACEFit: a fitted PACE model
stashPACE Stash PACE readouts in a SpatialExperiment
topDrivers Per-pair driver tables
topDrivers-method Per-pair driver tables
topDrivers<- Per-pair driver tables
topDrivers<--method Per-pair driver tables
varianceDecomposition Per-gene variance decomposition
varianceDecomposition-method Per-gene variance decomposition
varianceDecomposition<- Per-gene variance decomposition
varianceDecomposition<--method Per-gene variance decomposition