Package 'SingleMoleculeFootprintingData'

Title: Data supporting the SingleMoleculeFootprinting pkg
Description: This Data package contains data objcets relevanat for the SingleMoleculeFootprinting package. More specifically, it contains one example of aligned sequencing data (.bam & .bai) necessary to run the SingleMoleculeFootprinting vignette. Additionally, we provide data that are essential for some functions to work correctly such as BaitCapture() and SampleCorrelation().
Authors: Guido Barzaghi [aut, cre] (ORCID: <https://orcid.org/0000-0001-6066-3920>), Arnaud Krebs [aut] (ORCID: <https://orcid.org/0000-0001-7999-6127>), Mike Smith [ctb] (ORCID: <https://orcid.org/0000-0002-7800-3848>)
Maintainer: Guido Barzaghi <guido.barzaghi@embl.de>
License: GPL-3
Version: 1.20.0
Built: 2026-10-10 11:14:33 UTC
Source: https://github.com/bioc/SingleMoleculeFootprintingData

Help Index


SingleMoleculeFootprintingData

Description

This Data package contains r objcets necessary to run some of the functions from the SingleMoleculeFootprinting package. SingleMoleculeFootprinting is an R package providing functions to analyze Single Molecule Footprinting (SMF) data.

Usage

NRF1pair.bam(metadata = FALSE)
NRF1pair.bam.bai(metadata = FALSE)
EnrichmentRegions_mm10.rds(metadata = FALSE)
ReferenceMethylation.rds(metadata = FALSE)
AllCs.rds(metadata = FALSE)

Arguments

metadata

FALSE (default) returns data. TRUE returns metadata

Value

Returns respectively: NRF1pair.bam - Bam file contanining reads covering example NRF1 pair binding locus used for SingleMoleculeFootprinting vignette. NRF1pair.bam.bai - Bam index file to Bam file used as example data in SingleMoleculeFootprinting vignette EnrichmentRegions_mm10.rds - GRanges obj of mouse genomic regions enriched for SMF signal in genome-wide capture experiments. Can be used to compute bait capture efficiency ReferenceMethylation.rds - Reference matrix of genome-wide bulk SMF values for published experiments in mouse cell lines AllCs.rds - GRanges obj referencing the genomic context cytosines for mm10

Examples

NRF1pair.bam(metadata = TRUE)
NRF1pair.bam.bai(metadata = TRUE)
EnrichmentRegions_mm10.rds(metadata = TRUE)
ReferenceMethylation.rds(metadata = TRUE)
AllCs.rds(metadata = TRUE)