Design-Aware Region and Block Detection for Cross-Array Longitudinal EWAS


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Documentation for package ‘crossarrayEWAS’ version 0.99.1

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as_granges Region or block calls as a GRanges
call_blocks Call blocks from the state posterior
call_regions Turn a denoised effect track into regions
comethylation_clusters Group adjacent probes that co-vary within subject
distance_penalty Distance-decaying penalty for the denoising step
ewas_blocks Call long-range methylation blocks from a methylation object
ewas_regions Call differentially methylated regions from a methylation object
fit_block_hsmm Distance-aware three-state hidden semi-Markov block model
fit_within Within-subject (fixed-effects) probe-level fit
fit_within_se Fit the within-subject exposure effect on a SummarizedExperiment
moderate_variance Empirical-Bayes shrinkage of per-probe residual variance
naive_permutation Permute the exposure across all samples
probe_coords Probe chromosome and position from an annotated object
read_f64 Read a raw float64 matrix written by the pipeline
sort_probes Order an object by probe position
stability_selection Subject-level stability selection
tv_denoise Total-variation denoising of a probe-level effect track
within_subject_permutation Permute the exposure within subject